A Variant in a MicroRNA Complementary Site in the 3′UTR of the KIT Oncogene Increases Risk of Acral Melanoma

MicroRNAs are small ~22nt single stranded RNAs that negatively regulate protein expression by binding to partially complementary sequences in the 3′UTRs of target gene mRNAs. Recently, mutations have been identified in both microRNAs and target genes that disrupt regulatory relationships, contribute...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Godshalk, Sirie E., Paranjape, Trupti, Nallur, Sunitha, Speed, William, Chan, Elcie, Molinaro, Annette M., Bacchiocchi, Antonella, Hoyt, Kathleen, Tworkoski, Kathryn, Stern, David F., Sznol, Mario, Ariyan, Stephan, Lazova, Rossitza, Halaban, Ruth, Kidd, Kenneth K., Weidhaas, Joanne, Slack, Frank J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069149/
https://ncbi.nlm.nih.gov/pubmed/21119596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.536
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