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Activation of Trk neurotrophin receptors in the absence of neurotrophins

Neurotrophins regulate neuronal cell survival and synaptic plasticity through activation of Trk receptor tyrosine kinases. Binding of neurotrophins to Trk receptors results in receptor autophosphorylation and downstream phosphorylation cascades. Here, we describe an approach to use small molecule ag...

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Detalles Bibliográficos
Main Authors: Lee, Francis S., Chao, Moses V.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC30691/
https://ncbi.nlm.nih.gov/pubmed/11248116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061020198
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