Potent Innate Immune Response to Pathogenic Leptospira in Human Whole Blood

BACKGROUND: Leptospirosis is caused by pathogenic spirochetes of the genus Leptospira. The bacteria enter the human body via abraded skin or mucous membranes and may disseminate throughout. In general the clinical picture is mild but some patients develop rapidly progressive, severe disease with a h...

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Main Authors: Goris, Marga G. A., Wagenaar, Jiri F. P., Hartskeerl, Rudy A., van Gorp, Eric C. M., Schuller, Simone, Monahan, Avril M., Nally, Jarlath E., van der Poll, Tom, van 't Veer, Cornelis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069077/
https://ncbi.nlm.nih.gov/pubmed/21483834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018279
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