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Potent Innate Immune Response to Pathogenic Leptospira in Human Whole Blood

BACKGROUND: Leptospirosis is caused by pathogenic spirochetes of the genus Leptospira. The bacteria enter the human body via abraded skin or mucous membranes and may disseminate throughout. In general the clinical picture is mild but some patients develop rapidly progressive, severe disease with a h...

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Autori principali: Goris, Marga G. A., Wagenaar, Jiri F. P., Hartskeerl, Rudy A., van Gorp, Eric C. M., Schuller, Simone, Monahan, Avril M., Nally, Jarlath E., van der Poll, Tom, van 't Veer, Cornelis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069077/
https://ncbi.nlm.nih.gov/pubmed/21483834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018279
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