Results of Antiretroviral Treatment Interruption and Intensification in Advanced Multi-Drug Resistant HIV Infection from the OPTIMA Trial

BACKGROUND: Guidance is needed on best medical management for advanced HIV disease with multidrug resistance (MDR) and limited retreatment options. We assessed two novel antiretroviral (ARV) treatment approaches in this setting. METHODS AND FINDINGS: We conducted a 2×2 factorial randomized open labe...

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Main Authors: Holodniy, Mark, Brown, Sheldon T., Cameron, D. William, Kyriakides, Tassos C., Angus, Brian, Babiker, Abdel, Singer, Joel, Owens, Douglas K., Anis, Aslam, Goodall, Ruth, Hudson, Fleur, Piaseczny, Mirek, Russo, John, Schechter, Martin, Deyton, Lawrence, Darbyshire, Janet
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069000/
https://ncbi.nlm.nih.gov/pubmed/21483491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014764
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