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Results of Antiretroviral Treatment Interruption and Intensification in Advanced Multi-Drug Resistant HIV Infection from the OPTIMA Trial

BACKGROUND: Guidance is needed on best medical management for advanced HIV disease with multidrug resistance (MDR) and limited retreatment options. We assessed two novel antiretroviral (ARV) treatment approaches in this setting. METHODS AND FINDINGS: We conducted a 2×2 factorial randomized open labe...

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Autori principali: Holodniy, Mark, Brown, Sheldon T., Cameron, D. William, Kyriakides, Tassos C., Angus, Brian, Babiker, Abdel, Singer, Joel, Owens, Douglas K., Anis, Aslam, Goodall, Ruth, Hudson, Fleur, Piaseczny, Mirek, Russo, John, Schechter, Martin, Deyton, Lawrence, Darbyshire, Janet
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069000/
https://ncbi.nlm.nih.gov/pubmed/21483491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014764
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