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Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity.
HAP1 protein, the major apurinic/apyrimidinic (AP) endonuclease in human cells, is a member of a homologous family of multifunctional DNA repair enzymes including the Escherichia coli exonuclease III and Drosophila Rrp1 proteins. The most extensively characterised member of this family, exonuclease...
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主要な著者: | , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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1995
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306895/ https://ncbi.nlm.nih.gov/pubmed/7784208 |
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