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Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity.

HAP1 protein, the major apurinic/apyrimidinic (AP) endonuclease in human cells, is a member of a homologous family of multifunctional DNA repair enzymes including the Escherichia coli exonuclease III and Drosophila Rrp1 proteins. The most extensively characterised member of this family, exonuclease...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Barzilay, G, Walker, L J, Robson, C N, Hickson, I D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 1995
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306895/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7784208/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.9.1544
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