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Formation of DNA triple helices inhibits DNA unwinding by the SV40 large T-antigen helicase.
Previous studies have indicated that d(TC)n.d(GA)n microsatellites may serve as arrest signals for mammalian DNA replication through the ability of such sequences to form DNA triple helices and thereby inhibit replication enzymes. To further test this hypothesis, we examined the ability of d(TC)i.d(...
Gespeichert in:
| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1995
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| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306852/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.8.1292 |
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