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Analysis of hepatocyte nuclear factor-3 beta protein domains required for transcriptional activation and nuclear targeting.

Three distinct hepatocyte nuclear factor 3 (HNF-3) proteins (alpha, beta and gamma) regulate transcription of the transthyretin (TTR) and numerous other liver-specific genes. The HNF-3 proteins bind DNA via a homologous winged helix motif common to a number of developmental regulatory proteins inclu...

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Detalles Bibliográficos
Main Authors: Qian, X, Costa, R H
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC306829/
https://ncbi.nlm.nih.gov/pubmed/7739897
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