Decreased expression of hepatocyte nuclear factor 3 alpha during the acute-phase response influences transthyretin gene transcription.

Three distinct hepatocyte nuclear factor 3 (HNF-3) proteins (alpha, beta, and gamma) are known to regulate the transcription of numerous liver-specific genes. The HNF-3 proteins bind to DNA as monomers through a winged-helix motif, which is also utilized by a number of developmental regulators, incl...

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Main Authors: Qian, X, Samadani, U, Porcella, A, Costa, R H
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC230360/
https://ncbi.nlm.nih.gov/pubmed/7862129
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