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Evidence for Enhanced Tissue Factor Expression in Age-related Macular Degeneration

Tissue factor (TF) is the primary initiator of blood coagulation. In addition to hemostasis, TF can initiate intracellular signaling and promote inflammation and angiogenesis, the key processes underlying the pathogenesis of age-related macular degeneration (AMD). AMD, the leading cause of irreversi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cho, Youngeun, Cao, Xiaoguang, Shen, DeFen, Tuo, Jingsheng, Parver, Leonard M., Rickles, Frederick R., Chan, Chi-Chao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068211/
https://ncbi.nlm.nih.gov/pubmed/21042291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.184
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