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Defining Network Topologies that Can Achieve Biochemical Adaptation
Many signaling systems show adaptation—the ability to reset themselves after responding to a stimulus. We computationally searched all possible three-node enzyme network topologies to identify those that could perform adaptation. Only two major core topologies emerge as robust solutions: a negative...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3068210/ https://ncbi.nlm.nih.gov/pubmed/19703401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.06.013 |
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