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Spontaneous Emergence of Multiple Drug Resistance in Tuberculosis before and during Therapy

The emergence of drug resistance in M. tuberculosis undermines the efficacy of tuberculosis (TB) treatment in individuals and of TB control programs in populations. Multiple drug resistance is often attributed to sequential functional monotherapy, and standard initial treatment regimens have therefo...

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Bibliographic Details
Main Authors: Colijn, Caroline, Cohen, Ted, Ganesh, Ayalvadi, Murray, Megan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068161/
https://ncbi.nlm.nih.gov/pubmed/21479171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018327
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