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Isoniazid Resistance and the Future of Drug-Resistant Tuberculosis

Bacterial chromosomal mutations that confer antibiotic resistance often have deleterious effects that impose costs on reproductive fitness. This observation has led to the generalization that in the absence of the selection pressure exerted through treatment, the frequency of resistance will decreas...

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Bibliographic Details
Main Authors: COHEN, TED, BECERRA, MERCEDES C., MURRAY, MEGAN B.
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652757/
https://ncbi.nlm.nih.gov/pubmed/15650371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mdr.2004.10.280
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