Statistical Interpretation of the RV144 HIV Vaccine Efficacy Trial in Thailand: A Case Study for Statistical Issues in Efficacy Trials

Recently, the RV144 randomized, double-blind, efficacy trial in Thailand reported that a prime-boost human immunodeficiency virus (HIV) vaccine regimen conferred ∼30% protection against HIV acquisition. However, different analyses seemed to give conflicting results, and a heated debate ensued as sci...

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Detalhes bibliográficos
Main Authors: Gilbert, Peter B., Berger, James O., Stablein, Donald, Becker, Stephen, Essex, Max, Hammer, Scott M., Kim, Jerome H., DeGruttola, Victor G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068028/
https://ncbi.nlm.nih.gov/pubmed/21402548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq152
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