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Spread of Herpes Simplex Virus to the Spinal Cord Is Independent of Spread to Dorsal Root Ganglia

Levels of herpes simplex virus 1 (HSV-1) and HSV-2 DNA in dorsal root ganglia (DRG) and spinal cord (SC) were quantified after inoculation of guinea pig genitals and footpads. In genital infection, viral DNA reached SC and DRG simultaneously (at 2 to 3 days after inoculation) but was more abundant i...

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Bibliographic Details
Main Authors: Ohashi, Masahiro, Bertke, Andrea S., Patel, Amita, Krause, Philip R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067948/
https://ncbi.nlm.nih.gov/pubmed/21159869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02426-10
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