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Effector CD4(+) T-Cell Involvement in Clearance of Infectious Herpes Simplex Virus Type 1 from Sensory Ganglia and Spinal Cords

In primary infection, CD8(+) T cells are important for clearance of infectious herpes simplex virus (HSV) from sensory ganglia. In this study, evidence of CD4(+) T-cell-mediated clearance of infectious HSV type 1 (HSV-1) from neural tissues was also detected. In immunocompetent mice, HSV-specific CD...

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Detalhes bibliográficos
Main Authors: Johnson, Alison J., Chu, Chin-Fun, Milligan, Gregg N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546982/
https://ncbi.nlm.nih.gov/pubmed/18667492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01159-08
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