S-adenosyl methionine alters the DNA contacts of the EcoKI methyltransferase.
The EcoKI methyltransferase methylates two adenines on opposite strands of its bipartite DNA recognition sequence AAC(N6)GTGC. The enzyme has a strong preference for hemimethylated DNA substrates, but the methylation state of the DNA does not influence its binding affinity. Methylation interference...
Uloženo v:
| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
1995
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| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7731811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.6.967 |
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