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S-adenosyl methionine alters the DNA contacts of the EcoKI methyltransferase.
The EcoKI methyltransferase methylates two adenines on opposite strands of its bipartite DNA recognition sequence AAC(N6)GTGC. The enzyme has a strong preference for hemimethylated DNA substrates, but the methylation state of the DNA does not influence its binding affinity. Methylation interference...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1995
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306793/ https://ncbi.nlm.nih.gov/pubmed/7731811 |
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