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Analysis of Human APOBEC3H Haplotypes and Anti-Human Immunodeficiency Virus Type 1 Activity

Human APOBEC3H (A3H) has one cytidine deaminase domain (CDD) and inhibits the replication of retrotransposons and human immunodeficiency virus type 1 (HIV-1) in a Vif-resistant manner. Human A3H has five single amino acid polymorphisms (N15Δ, R18L, G105R, K121D, and E178D), and four haplotypes (I to...

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Bibliographic Details
Main Authors: Wang, Xiaojun, Abudu, Aierken, Son, SungMo, Dang, Ying, Venta, Patrick J., Zheng, Yong-Hui
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067873/
https://ncbi.nlm.nih.gov/pubmed/21270145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02049-10
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