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Complementing Defective Viruses That Express Separate Paramyxovirus Glycoproteins Provide a New Vaccine Vector Approach

Replication-defective vaccine vectors based on vesicular stomatitis virus (VSV) lacking its envelope glycoprotein gene (G) are highly effective in animal models. However, such ΔG vectors are difficult to grow because they require complementation with the VSV G protein. In addition, the complementing...

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Autors principals: Chattopadhyay, Anasuya, Rose, John K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067786/
https://ncbi.nlm.nih.gov/pubmed/21177820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01852-10
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