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Complementing Defective Viruses That Express Separate Paramyxovirus Glycoproteins Provide a New Vaccine Vector Approach

Replication-defective vaccine vectors based on vesicular stomatitis virus (VSV) lacking its envelope glycoprotein gene (G) are highly effective in animal models. However, such ΔG vectors are difficult to grow because they require complementation with the VSV G protein. In addition, the complementing...

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Detalhes bibliográficos
Main Authors: Chattopadhyay, Anasuya, Rose, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067786/
https://ncbi.nlm.nih.gov/pubmed/21177820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01852-10
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