Novel system for analysis of group I 3' splice site reactions based on functional trans-interaction of the P1/P10 reaction helix with the ribozyme's catalytic core.

A group I intron from a bacterial tRNA precursor has been converted into an RNA enzyme that catalyzes the efficient polymerization of oligoribonucleotide analogs of tRNA exons using a reaction scheme consisting of multiple cycles of reverse and forward exon ligation reactions. Here, we present resul...

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Bibliographic Details
Main Authors: Chowrira, B M, Berzal-Herranz, A, Burke, J M
Format: Artigo
Language:Inglês
Published: 1995
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC306769/
https://ncbi.nlm.nih.gov/pubmed/7708502
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