DNA bending by thyroid hormone receptor: influence of half-site spacing and RXR.

Transcriptional activation by thyroid hormone (T3) requires interactions between the T3 receptor (TR) and T3 response elements (TREs) composed of two copies of sequences related to AGGTCA. Direct repeats of this sequence are a functional TRE when spaced by 4 but not by 5 bp (DR4 versus DR5). TR boun...

Full description

Saved in:
Bibliographic Details
Main Authors: Shulemovich, K, Dimaculangan, D D, Katz, D, Lazar, M A
Format: Artigo
Language:Inglês
Published: 1995
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC306764/
https://ncbi.nlm.nih.gov/pubmed/7708497
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items