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Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor.

The retinoid X receptor (RXR) heterodimerizes with a variety of nuclear receptors. In addition, RXR forms homodimers in the presence of its ligand, 9-cis-retinoic acid. From deletion and point mutation analysis we present evidence that a short region (amino acids 413 to 443) in the carboxy terminus...

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Detalhes bibliográficos
Main Authors: Zhang, X K, Salbert, G, Lee, M O, Pfahl, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC358797/
https://ncbi.nlm.nih.gov/pubmed/8196667
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