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Cholesterol Is Not an Essential Source of Nutrition for Mycobacterium tuberculosis during Infection
Rv1106c (hsd; 3β-hydroxysteroid dehydrogenase) is required by Mycobacterium tuberculosis for growth on cholesterol as a sole carbon source, whereas Rv3409c is not. Mutation of Rv1106c does not reduce Mycobacterium tuberculosis growth in infected macrophages or guinea pigs. We conclude that cholester...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067635/ https://ncbi.nlm.nih.gov/pubmed/21257778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01210-10 |
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