Differential Microbicidal Effects of Human Histone Proteins H2A and H2B on Leishmania Promastigotes and Amastigotes

Recent studies have shown that histone proteins can act as antimicrobial peptides in host defense against extracellular bacteria, fungi, and Leishmania promastigotes. In this study, we used human recombinant histone proteins to further study their leishmaniacidal effects and the underlying mechanism...

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Autori principali: Wang, Yingwei, Chen, Yang, Xin, Lijun, Beverley, Stephen M., Carlsen, Eric D., Popov, Vsevolod, Chang, Kwang-Poo, Wang, Ming, Soong, Lynn
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067510/
https://ncbi.nlm.nih.gov/pubmed/21189319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00658-10
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