Destabilization of YopE by the Ubiquitin-Proteasome Pathway Fine-Tunes Yop Delivery into Host Cells and Facilitates Systemic Spread of Yersinia enterocolitica in Host Lymphoid Tissue

Pathogenic Yersinia species inject a panel of Yop virulence proteins by type III protein secretion into host cells to modulate cellular defense responses. This enables the survival and dissemination of the bacteria in the host lymphoid tissue. We have previously shown that YopE of the Y. enterocolit...

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Autores principales: Gaus, Kristin, Hentschke, Moritz, Czymmeck, Nicole, Novikova, Lena, Trülzsch, Konrad, Valentin-Weigand, Peter, Aepfelbacher, Martin, Ruckdeschel, Klaus
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067501/
https://ncbi.nlm.nih.gov/pubmed/21149597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00694-10
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