Reduction of Immunogenicity of Anthrax Vaccines Subjected to Thermal Stress, as Measured by a Toxin Neutralization Assay

We report that a toxin neutralization assay (TNA) can detect a decrease in the immunogenicity of anthrax vaccines as a consequence of brief exposure to elevated temperature. This attribute of TNA may help in adopting immunogenicity as a replacement of the current potency test, which involves protect...

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Detaylı Bibliyografya
Asıl Yazarlar: Castelán-Vega, Juan, Corvette, Laura, Sirota, Lev, Arciniega, Juan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2011
Konular:
Vaccine Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067352/
https://ncbi.nlm.nih.gov/pubmed/21147935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00267-10
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