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In Vitro Activities of New 2-Substituted Quinolines against Leishmania donovani

A series of 9 quinolines and 18 styrylquinolines was evaluated for the drugs' in vitro antileishmanial activities and cytotoxicities. The 7-aroylstyrylquinoline scaffold appeared to be the most promising one, with the most interesting compound, no. 35, exhibiting a 50% inhibitory concentration...

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Autori principali: Loiseau, Philippe M., Gupta, Suman, Verma, Aditya, Srivastava, Saumya, Puri, S. K., Sliman, Faten, Normand-Bayle, Marie, Desmaele, Didier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067194/
https://ncbi.nlm.nih.gov/pubmed/21220526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01299-10
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