In Vitro Pharmacodynamics of Simulated Pulmonary Exposures of Tigecycline Alone and in Combination against Klebsiella pneumoniae Isolates Producing a KPC Carbapenemase

Multidrug-resistant Klebsiella pneumoniae strains that produce a serine carbapenemase (KPC) are emerging worldwide, with few therapeutic options that retain consistent susceptibility. The objective of this study was to determine the effect of combination therapy with tigecycline versus tigecycline a...

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Bibliografiska uppgifter
Huvudupphovsmän: Wiskirchen, Dora E., Koomanachai, Pornpan, Nicasio, Anthony M., Nicolau, David P., Kuti, Joseph L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2011
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067181/
https://ncbi.nlm.nih.gov/pubmed/21282442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01253-10
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