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Predicting In Vitro Antibacterial Efficacy across Experimental Designs with a Semimechanistic Pharmacokinetic-Pharmacodynamic Model

We have previously described a general semimechanistic pharmacokinetic-pharmacodynamic (PKPD) model that successfully characterized the time course of antibacterial effects seen in bacterial cultures when exposed to static concentrations of five antibacterial agents of different classes. In this PKP...

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Detalles Bibliográficos
Main Authors: Nielsen, Elisabet I., Cars, Otto, Friberg, Lena E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067154/
https://ncbi.nlm.nih.gov/pubmed/21282424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01286-10
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