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Enzymatically Modified Low-Density Lipoprotein Is Recognized by C1q and Activates the Classical Complement Pathway

Several studies suggest that the complement system is involved in atherogenesis. To further investigate this question, we have studied the ability of native and modified forms of LDL to bind and activate C1, the complex protease that triggers the classical pathway of complement. Unlike native LDL, o...

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Autori principali: Arlaud, Gérard J., Biro, Adrienn, Ling, Wai Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066639/
https://ncbi.nlm.nih.gov/pubmed/21490800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/376092
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