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CCR5 Knockout Strategies

PURPOSE OF REVIEW: Individuals homozygous for a deletion in the CCR5 gene (CCR5Δ32) are almost completely resistant to HIV-1 infection. A recent report that transplantation of hematopoietic stem/progenitor cells (HSC) from a CCR5Δ32 homozygous donor effectively cured an HIV patient has increased int...

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Detalhes bibliográficos
Main Authors: Cannon, Paula, June, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066441/
https://ncbi.nlm.nih.gov/pubmed/21242897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0b013e32834122d7
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