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Impaired cell cycle regulation of osteoblast-related transcription factor Runx2/Cbfa1 in osteosarcoma cells
In mammals, bone differentiation requires the functional expression of the Runx2/Cbfβ heterodimeric complex. Our previous results indicate that Runx2 is also a suppressor of pre-osteoblast proliferation by affecting cell cycle progression at G(1). Runx2 levels are cell cycle regulated, oscillating f...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066433/ https://ncbi.nlm.nih.gov/pubmed/19739101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21894 |
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