Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene

Evidence suggests that de novo, therapy-related and benzene-induced acute myeloid leukemias (AML) occur via similar cytogenetic and genetic pathways, several of which involve aneuploidy, the loss or gain of chromosomes. Aneuploidy of specific chromosomes has been detected in benzene-related leukemia...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Luoping, Lan, Qing, Guo, Weihong, Hubbard, Alan E., Li, Guilan, Rappaport, Stephen M., McHale, Cliona M., Shen, Min, Ji, Zhiying, Vermeulen, Roel, Yin, Songnian, Rothman, Nathaniel, Smith, Martyn T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Carcinogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066415/
https://ncbi.nlm.nih.gov/pubmed/21216845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq286
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