Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene

Evidence suggests that de novo, therapy-related and benzene-induced acute myeloid leukemias (AML) occur via similar cytogenetic and genetic pathways, several of which involve aneuploidy, the loss or gain of chromosomes. Aneuploidy of specific chromosomes has been detected in benzene-related leukemia...

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Autors principals: Zhang, Luoping, Lan, Qing, Guo, Weihong, Hubbard, Alan E., Li, Guilan, Rappaport, Stephen M., McHale, Cliona M., Shen, Min, Ji, Zhiying, Vermeulen, Roel, Yin, Songnian, Rothman, Nathaniel, Smith, Martyn T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Carcinogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066415/
https://ncbi.nlm.nih.gov/pubmed/21216845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq286
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