On the mechanism of preferential incorporation of dAMP at abasic sites in translesional DNA synthesis. Role of proofreading activity of DNA polymerase and thermodynamic characterization of model template-primers containing an abasic site.

DNA polymerase preferentially incorporate dAMP opposite abasic sites (A-rule). The mechanism of the A-rule can be studied by analyzing three dissected stages of the reaction including (i) initial nucleotide insertion, (ii) proofreading excision of the inserted nucleotide and (iii) extension of the n...

Full description

Saved in:
Bibliographic Details
Main Authors: Ide, H, Murayama, H, Sakamoto, S, Makino, K, Honda, K, Nakamuta, H, Sasaki, M, Sugimoto, N
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC306639/
https://ncbi.nlm.nih.gov/pubmed/7870577
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items