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Prolonged Intragastric Drug Delivery Mediated by Eudragit(®)E-Carrageenan Polyelectrolyte Matrix Tablets
Interpolyelectrolyte (IPE) complexation between carrageenan (CG) and Eudragit E (EE) was studied in 0.1 M HCl and was used to develop floating matrix tablets aimed to prolong gastric-residence time and sustain delivery of the loaded drug. The optimum EE/CG IPE complexation weight ratio (0.6) was det...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer US
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066363/ https://ncbi.nlm.nih.gov/pubmed/21302009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9595-0 |
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