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Prolonged Intragastric Drug Delivery Mediated by Eudragit(®)E-Carrageenan Polyelectrolyte Matrix Tablets

Interpolyelectrolyte (IPE) complexation between carrageenan (CG) and Eudragit E (EE) was studied in 0.1 M HCl and was used to develop floating matrix tablets aimed to prolong gastric-residence time and sustain delivery of the loaded drug. The optimum EE/CG IPE complexation weight ratio (0.6) was det...

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Detalhes bibliográficos
Main Authors: Bani-Jaber, Ahmad, Al-Aani, Leena, Alkhatib, Hatim, Al-Khalidi, Bashar
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066363/
https://ncbi.nlm.nih.gov/pubmed/21302009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9595-0
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