Antisense 2'-O-alkyl oligoribonucleotides are efficient inhibitors of reverse transcription.
Reverse transcription is one step of the retroviral development which can be inhibited by antisense oligonucleotides complementary to the RNA template. 2'-O-Alkyl oligoribonucleotides are of interest due to their nuclease resistance, and to the high stability of the hybrids they form with RNA. Oligo...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7532858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.1.64 |
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