Synthesis and in vivo evaluation of (S)-6-(4-fluorophenoxy)-3-((1-[(11)C]methylpiperidin-3-yl)methyl)-2-o-tolylquinazolin-4(3H)-one, a potential PET tracer for growth hormone secretagogue receptor (GHSR)

The peptide hormone ghrelin mediates through action on its receptor, the growth hormone secretagogue receptor (GHSR), and is known to play an important role in a variety of metabolic functions including appetite stimulation, weight gain and suppression of insulin secretion. In light of the fact that...

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Главные авторы: Potter, Rachel, Horti, Andrew G., Ravert, Hayden T., Holt, Daniel P., Finley, Paige, Scheffel, Ursula, Dannals, Robert F., Wahl, Richard L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066299/
https://ncbi.nlm.nih.gov/pubmed/21388815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.02.021
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