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Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases.

Successes in classical gene therapies have been achieved by placing a corrected copy of a defective nuclear gene in cells. A similar gene replacement approach for a mutant mitochondrial genome is invariably linked to the use of a yet unavailable mitochondrial transfection vector. Here we show that D...

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Detalhes bibliográficos
Main Authors: Seibel, P, Trappe, J, Villani, G, Klopstock, T, Papa, S, Reichmann, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC306624/
https://ncbi.nlm.nih.gov/pubmed/7870573
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