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Impaired Attention in the 3xTgAD Mouse Model of Alzheimer's Disease: Rescue by Donepezil (Aricept)

Several mouse models of Alzheimer's disease (AD) with abundant β-amyloid and/or aberrantly phosphorylated tau develop memory impairments. However, multiple non-mnemonic cognitive domains such as attention and executive control are also compromised early in AD individuals. Currently, it is uncle...

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Bibliographic Details
Main Authors: Romberg, Carola, Mattson, Mark P., Mughal, Mohamed R., Bussey, Timothy J., Saksida, Lisa M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066152/
https://ncbi.nlm.nih.gov/pubmed/21368062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5242-10.2011
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