The plasma membrane redox system is impaired by amyloid β-peptide and in the hippocampus and cerebral cortex of 3xTgAD mice

Membrane-associated oxidative stress has been implicated in the synaptic dysfunction and neuronal degeneration that occurs in Alzheimer’s disease (AD), but the underlying mechanisms are unknown. Enzymes of the plasma membrane redox system (PMRS) provide electrons for energy metabolism and recycling...

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Autores principales: Hyun, Dong-Hoon, Mughal, Mohamed R., Yang, Hyunwon, Lee, Ji Hyun, Ko, Eun Joo, Hunt, Nicole D., de Cabo, Rafael, Mattson, Mark P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946538/
https://ncbi.nlm.nih.gov/pubmed/20673763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.07.020
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