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Cutting Edge: Helminth Infection Induces IgE in the Absence of μ- or δ-Chain Expression
Infections with helminth parasites are associated with an IgE isotype switch and high serum IgE concentrations. IgE is rapidly bound by the high affinity IgE receptor (FcεRI), thereby sensitizing FcεRI-bearing basophils and mast cells for IgE-inducible effector functions such as IL-4 production. The...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066072/ https://ncbi.nlm.nih.gov/pubmed/18981085 |
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