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Understanding the Role of the Death Receptor 5/FADD/caspase-8 Death Signaling in Cancer Metastasis

The normal function of the extrinsic apoptotic pathway is to mediate apoptosis. Thus, this pathway is generally recognized to be critical in host immune surveillance against cancer. However, many studies have suggested that some key components in this pathway including Fas, death receptor 5 (DR5), F...

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Библиографические подробности
Главный автор: Sun, Shi-Yong
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066014/
https://ncbi.nlm.nih.gov/pubmed/21461184
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