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Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8

The MutM [formamidopyrimidine DNA glycosylase (Fpg)] protein is a trifunctional DNA base excision repair enzyme that removes a wide range of oxidatively damaged bases (N-glycosylase activity) and cleaves both the 3′- and 5′-phosphodiester bonds of the resulting apurinic/apyrimidinic site (AP lyase a...

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Bibliografiske detaljer
Main Authors: Sugahara, Mitsuaki, Mikawa, Tsutomu, Kumasaka, Takashi, Yamamoto, Masaki, Kato, Ryuichi, Fukuyama, Keiichi, Inoue, Yorinao, Kuramitsu, Seiki
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC306600/
https://ncbi.nlm.nih.gov/pubmed/10921868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.3857
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