Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8

The MutM [formamidopyrimidine DNA glycosylase (Fpg)] protein is a trifunctional DNA base excision repair enzyme that removes a wide range of oxidatively damaged bases (N-glycosylase activity) and cleaves both the 3′- and 5′-phosphodiester bonds of the resulting apurinic/apyrimidinic site (AP lyase a...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Sugahara, Mitsuaki, Mikawa, Tsutomu, Kumasaka, Takashi, Yamamoto, Masaki, Kato, Ryuichi, Fukuyama, Keiichi, Inoue, Yorinao, Kuramitsu, Seiki
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2000
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10921868/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.15.3857
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